8 October 2013
MELODI Workshop Opening Ceremony
Moderator: Frank Hardeman (SCK•CEN, BE)
SCK•CEN  Frank Hardeman
Horizon 2020, Euratom and Radiation Research Bruno Schmitz (EC)
WHO  Ausra Kesminiene
ICRP William F. Morgan
MELODI Jacques Repussard
Moderator: Frank Hardeman (SCK•CEN, BE) and Thomas Jung (BfS, DE)
Session Sponsored by MELODI, ALLIANCE,
ALLIANCE 1st SRA/Priorities Hildegarde Vandenhove (SCK•CEN, BE)
NERIS 1st SRA/Priorities Wolfgang Raskob (KIT, DE)
EURADOS 1st SRA/Priorities Werner Rühm (HMGU, DE)
MELODI 4th SRA/Priorities Dietrich Averbeck (IRSN/CEA, FR)
Fukushima: Emergency, Dosimetry, Environment, Health
Moderators: Jean-René Jourdain (IRSN, F) & Johan Camps (SCK•CEN, BE)
Session Sponsored by COMET
UNSCEAR Fukushima Report : UNSCEAR's Assessment of Levels and Effects of Radiation Exposure due to the Nuclear Accident after the 2011 Great East-Japan Earthquake and Tsunami Jean-René Jourdain (IRSN, FR)
WHO Fukushima Report Richard Wakeford (UMan, UK)
Ultrasonography Surveys and Thyroid Cancer after the Fukushima Accident Peter Jacob (HMGU, DE)
Response of SCK•CEN to the Fukushima Nuclear Accident in the Context of the Protection of Belgian Citizens Johan Camps (SCK•CEN, BE)
Cytogenetic Analysis of Restoration Workers for Fukushima Daiichi Nuclear Power Station Accident Yumiko Suto (NIRS, JP)
A Possible Warning from Fukushima: A Preliminary Analysis of Radiation Dose and Occurrence of Thyroid Nodules Using City and Village Level Data” is accepted in the session “Fukushima: Emergency, Dosimetry, Environment, Health Yutaka Hamaoka
(Keio University, JP)
Improvement on Collaboration on Infrastructures and Biobanks Available within EU Projects
Moderators: Laurence Sabatier (CEA, FR) & Liviu-Cristian Mihailescu (SCK•CEN, BE)
Irradiations Facilities for Biological Samples – Towards the Ideal Installation Liviu-Cristian Mihailescu (SCK•CEN, BE)
Survey on Existing Infrastructures, Analysis of Platforms Including High-Throughput Technologies William Hempel (CEA, FR)
Determining the Most Appropriate Cohorts for Low Dose Research Purposes: a Multidimensional Puzzle Eileen Pernot (CREAL, ES)
Study of Radiation Related Cardiovascular Diseases (CVD) Using Animal Models Norio Takahashi (RERF, JP)
Chernobyl Tissue Bank – a Quality Assured Resource for Systems Biology of Radiation Induced Thyroid Cancer Gerry A. Thomas
(Charing Cross Hospital, GB)
DoReMi Education & Training Forum
Moderators: Michèle Coeck (SCK•CEN, BE) and Andrea Ottolenghi (UP, IT)
Session Sponsored by DoReMi
Welcome Andrea Ottolenghi (UP, IT)
Introduction to the Forum Purposes & Themes Vere Smyth (UP, IT)
What Should We Be Focussing On? Vere Smyth (UP, IT)
What Was Originally Intended by HLEG? Mike Atkinson (HMGU, DE)
E&T for Life-long-learning and Continuous Professional Development (CPD) George Van Goethem (EC)
E&T for Radiation Protection: EUTERP Initiatives Michèle Coeck (SCK•CEN, BE)
E&T Initiatives in the SRAs of the Other Technology Platforms:
Deborah Oughton
Wolfgang Raskob
Werner Rühm
Moderators: Sisko Salomaa (STUK, FI) & Hans Vanmarcke (SCK•CEN, BE)
UNSCEAR White Paper: Biological Mechanisms of Radiation Actions at Low Doses  
Bouffler_UNSCEAR White Paper Presentation - Presentation Bouffler - UNSCEAR White Paper
Simon Bouffler (PHE, UK)
Article 31 RIHSS Report on Individual Radiosensitivity Patrick Smeesters
(former FANC, BE)
UNSCEAR Report on Attribution of Health Effects Wolfgang Müller (UEssen, DE)
Radiation Effects on Wildlife
Moderators: Hildegarde Vandenhove (SCK•CEN, BE) & Thomas Hinton (IRSN, FR)
Session Sponsored by STAR
Effect of Fukushima-Derived Radionuclides on the Physiology and Phenotype Expression of Birds Living in the Fukushima 80 km Area Christelle Adam (IRSN, FR)
From Lab-based Ecotoxicity Tests Towards Evaluating Radiation Protection Criteria for Wildlife: Lemna Minor as an Example Nele Horemans (SCK•CEN, BE)
The Cosmic Silence Experiment: Modulation of Stress Response Mechanisms in Living Systems Exposed to Different Radiation Environments Maria Antonella Tabocchini
Lifetime Study in Mice: Low-dose Radiation Cataracts and Further Non-cancer Effects Claudia Dalke (HMGU, DE)
DoReMi Education & Training Forum
Moderators: Michèle Coeck (SCK•CEN, BE) and Andrea Ottolenghi (UP, IT)
Session Sponsored by DoReMi
Survival in a Changing Environment Vere Smyth (UP, IT)
E&T in Horizon 2020 George Van Goethem (EC)
Scope and Strategy of the European Nuclear Education Network Walter Ambrosini (UP, IT)
The Development of a MELODI Policy for E&T Thomas Jung (BFS, DE)
E&T in DoReMi, MELODI and OPERRA Andrea Ottolenghi (UP, IT)
9 October 2013
MELODI Recent Developments – MELODI Award Ceremony
Summary of the Former Day
Moderators: Bernd Grossche (BfS, DE) & Maria Blettner (Umainz, DE)
Sponsored by BfS
MELODI Recent Developments Jacques Repussard (IRSN, FR)
MELODI Award Presentation: 3-D Skin and Lung Epithelial Models for Radiation Biology Studies Anna Acheva (STUK, FI)
MELODI Award Presentation: Systems Radiation Biology to Model Non-linear Effects Luca Mariotti (UP, IT)
Plenary: Radiation Effects on Human Health
Moderators: Sarah Baatout (SCK•CEN, BE) & Maria Blettner (Umainz, DE)
Sponsored by BfS
Strategic Research towards Cognitive and Cerebrovascular Effects of Radiation Rafi Benotmane (SCK•CEN, BE)
Exposure of the Eye Lens and Cataract Risk Roy Shore (RERF, JP)
Heart Disease after Radiotherapy in Breast Cancer Patients Sarah Darby (Oxford U, UK)
The Expression of Long Non-coding RNAs is Influenced by Exposure to Low Dose Irradiation Nataša Anastasov (HMGU, DE)
Open Discussion about the Importance of Genetics and Epigenetics within the MELODI Strategic Agenda Moderators: Roel Quintens and Nataša Anastasov
New Developments in Dosimetry
Moderators: Filip Vanhavere (SCK•CEN, BE) & Werner Rühm (HMGU, DE)
Session Sponsored by EURADOS
Operational Dose Quantities for External Radiation Exposure - Deficiencies and Options David Bartlett (former PHE, UK)
Towards a Quantification of Radiation Quality by Nanodosimetry Hans Rabus (PTB, DE)
Dose Distribution of Alpha and Auger-emitters in Lungs and Kidneys and at Cellular Level Weibo Li (HMGU, DE)
Eye lens dosimetry: Results from the ELDO Project Lara Struelens (SCK•CEN, BE)
Dosimetry in Diagnostic Medical Imaging: State of the Art and New Developments Annalisa Trianni (AOUUD, IT)
Device Dependent Exposure and Quality of Imaging in Computed Tomography Examinations Eeva Salminen (STUK, FI)
The Use of a Graphics Library in Multisource Modelling for Out-of-field Head Scatter Assessment Jérémi Vu Bezin (Inserm, FR)
The European Medical ALARA Network (EMAN) Padovani Renato (EFOMP, IT)
Mixed Exposure
Moderators: Nele Horemans (SCK•CEN, BE) & Per Eriksson (Uppsala University, SE)
Testing Radiation Effects in a Multiple Contaminant Context: an Overview of Different Concepts to Predict Mixture Toxicity Nele Horemans (SCK•CEN, BE)
Trans-generational Radiation-Induced Chromosomal Instability in the Female Enhances the Action of Chemical Mutagens Aurora Ruiz-Herrera (UAB, ES)
Combined Radiation and Chemotherapy Eeva Salminen (STUK, FI)
Co-exposure to Gamma Radiation and Nicotine During a Critical Period of Neonatal Brain Development Can Enhance Cognitive Defects in Adult Mice Per Eriksson
(Uppsala University, SE)
Genotoxic and Reproductive Effects of Chronic Low dose-rate Gamma-irradiation and Reduced Selenium Status in Repair-deficient Male Mice (Ogg1-/-) Ann-Karin Olsen (NIPH, NO)
High-Throughput Technologies: Advantages, Limitations and Future Challenges
Moderators: Hussein el-Saghire (SCK•CEN, BE) & Leon Mullenders (LUMC, NL)
MELODI SRA and the Integration of High-Throughput Technologies as Central Players in Low Dose Research Hussein el-Saghire (SCK•CEN, BE)
Gene Expression to Elucidate the Biological Impact of Low and Very Low Doses of Ionizing Radiation: a Hurdle Race Gaëtan Gruel (IRSN, FR)
Radiogenomics and Adverse Effects in Radiotherapy Patients Hubert Thierens (UGent, BE),
Modelling Low Dose and Chronic Irradiations Alessandro Campa (ISS, IT)
Radiopharmaceuticals and Radiotherapy
Moderators: Nathalie Impens (SCK•CEN, BE) & Tony Lahoutte (VUB, BE)
Molecular Radiotherapy: How Much Dose is the Patient Really Getting? Vere Smyth (UP, IT)
Special Requirements in the Development of Biokinetic Models for Radiopharmeceuticals Dietmar Nosske (BfS, DE)
Towards a DTPA-Therapy Model Bastian Breustedt (KIT, DE)
Transcriptional Effects on Normal Tissues after Administration of 211At in Mice Eva Forssell-Aronsson (Gothenburg Univ., SE)
Dosimetry and Radiobiology for Peptide Receptor Radionuclide Therapy (PRRT) Mark Konijnenberg
(Erasmus MC, NL)
Prenatal, Young Age Exposure and Transgenerational Effects on Animals and Plants
Moderators: Hanane Derradji (SCK•CEN, BE) & Patrick Smeesters (former FANC, BE)
Current Knowledge on Radiation-induced Effects of Prenatal Exposure and Transgenerational Effects: a Precautionary Perspective Patrick Smeesters
(former FANC, BE)
Developmental Effects and Chromosomal Instability after Irradiation of Early Mammalian Embryos Paul Jacquet (SCK•CEN, BE)
The Dose and Dose-rate Effects of Paternal Irradiation on Transgenerational Instability in Mice: a Radiotherapy Connection Yuri Dubrova (LU, UK)
A Worm’s Eye View of Trans-generational Effects Deborah Oughton (UMB, NO)
Risk Communication and Risk Perception: How Can Science Help Us?
Moderator: Tanja Perko (SCK•CEN)

Do we know how to communicate scientific uncertainty, radiation units, risk probabilities? Can social science and humanities enhance our understanding of radiological risk perception? All this and more on the FP7 OPERRA workshop exploring the needs for future research on perception and communication of radiation risks in the domain of low doses and medical use of ionizing radiation. The purpose is to lay the foundation for a discussion between social, human and natural sciences. The main challenges and gaps will be highlighted by invited speakers involved in both theoretical research and practice, and then the floor will be yours. Together we will try to identify the main issues, as well as potential topics for new research related to risk perception and risk communication. These topics would be included by the European Commission in the programme calls concerning the radiation research area.

Booth_MELODI Workshop
Drotz_Sjöberg_MELODI Workshop
Perko_Melodi 2013_Workshop

Keynote Speakers: Britt-Marie Drottz-Sjöberg and Peter Booth
10 October 2013
Plenary: Radiation Protection Issues
Moderators: Rafi Benotmane (SCK•CEN, BE) & Peter Jacob (HMGU, DE)
Session Sponsored by MELODI and IRSN
Current Approaches in Risk-based Evaluation of Chemical Carcinogens Andrea Hartwig (KIT, DE)
Cancer Risk from Exposure to 100 mSv within 5 Years Mary Schubauer-Berigan
Retrospective Dosimetry Concepts for Triage / Emergency Situations – Status and Future Needs Paola Fattibene (ISS, IT)
Heavy Ions: Space & Radiotherapy
Moderators: Marjan Moreels (SCK•CEN, BE) and Winok De Vos (UGent, BE)
Introduction to Charged Particles: Bridging the Gap between Earth and Space Marjan Moreels (SCK•CEN, BE)
DLR Solar Particle Events in Aviation and Space Gunther Reitz (DLR, DE)
Secondary Neutrons in Proton and Ion Therapy Liliana Stolarczyk (IFJ, PL)
Time-dependent Changes in Expression of Motility Genes in Prostate Cancer Cells after Exposure to Low- and High-let Radiation Annelies Suetens (SCK•CEN, BE)
The ANDANTE Project: a Multidisciplinary Approach to neutron RBE Andrea Ottolenghi (UP, IT)
Systems Biology
Moderators: William F. Morgan (PNNL, USA) & Pieter Monsieurs (SCK•CEN, BE)
Network Failure Modes of the Cellular Regulatory System in Cancer: a Statistical Perspective Wessel Van Wieringen (VU University MC, NL)
Differential in vivo Responses of Distinct Epidermal Stem Cells to Low Dose Irradiation Peggy Sotiropoulou (UCL, BE)
The transcriptional Response to Irradiation: Time to Move the Focus from Cellular to Tissutal Level Rodolfo Negri
(Sapienza Univ. of Rome, IT)
RENEB – Progress of the Biodose Network Ulrike Kulka (BfS, DE)
Mechanisms and Underlying Effects of Cancer and Non-cancer Effects
Moderators: An Aerts (SCK•CEN, BE) & Dietrich Averbeck (IRSN/CEA, FR)
Session Sponsored by CEREBRAD and PROCARDIO
(i) Recommendations from the MELODI SRA (ii) Acute versus Chronic Effects: How Comparable are They? An Aerts (SCK•CEN, BE)
PPAR Alpha is a Novel Radiation Target in Exposed Human and Murine Cardiac Tissue Soile Tapio (HMGU, DE)
Gene Expression and Mechanistic Studies on Blood Cells after Exposure to Low Doses of Ionizing Radiation: in vitro and in vivo Human Studies  Hussein el-Saghire (SCK•CEN, BE)
Evidence for a Direct Relationship between the Response to Irradiationand the Metabolic Profile of Tumor Cells Vanessa Bol (UCL, BE)
Effects of Low Dose Ionizing Radiation on the Neuronal Dopaminergic System and their Relevance for Parkinson’s Disease Pier G. Mastroberardino
(Erasmus Univ. MC, NL)
Low and Intermediate Dose Ionising Radiation Even Up to 2Gy Does Not Alter Viability and Phagocytic Behaviour of Activated Macrophages but Induces an Anti-inflammatory Cytokine Milieu Roland Wunderlich
(Friedrich-Alexander Univ., DE)
Internal Emitters
Moderators: Hilde Engels (SCK•CEN, BE) & Dominique Laurier (IRSN, FR)
Introduction: Current Issues Related to Internal Emitters Hilde Engels (SCK•CEN, BE)
Health Effects of Internal Alpha Emitters, Dosimetry James Marsh (PHE, UK)
Health Effects of Internal Alpha Emitters, Contribution of Epidemiology Margot Tirmache (ASN, FR)
Comparison of Physical and Biological Dosimetry for Internal Emitters Kai Rothkamm (PHE, UK)
Concerted Action for an Integrated (biologydosimetry-epidemiology) Research Project on Occupational Uranium Exposure Dominique Laurier (IRSN, FR)
Mortality from Internal and External Radiation Exposure in a Cohort of German Uranium Processing Workers, 1946-2008 Michaela Kreuzer (BfS, DE)
Differential  Effects of Chronic Internal 137Cs Contamination on Early and Intermediate Stages of Atherosclerosis in APOE-/- Mice Teni Ebrahimian (IRSN, FR)
The Meaning of Ethics for Radiological Protection Research and Research Policy
Moderator: Gaston Meskens (SCK•CEN)
The aim of this workshop is to organise a first reflection on the meaning of ethics for radiological protection research and research policy, and this for all relevant application contexts (nuclear energy, medical, industry). We aim to map the meaningful notions of ethics in relation to RP practice, research and policy, taking into account that we do not only consider the ‘ethical implications’ of potentially adverse effects of applications of nuclear technology, but also (and primarily) the ethical aspects of the justification of practices that involve nuclear technology. The workshop will consist of presentations and a general informal dialogue with all attendants. We invite all the MELODI Workshop participants to join us for this unique event. The workshop will result in a synthesis document that will be shared with the MELODI/OPERRA community and with other European relevant research networks. We will invite feedback and collect and synthesise comments to be discussed in the next workshop in Budweis in June 2014. The workshop will be moderated by Gaston Meskens (Belgian Nuclear Research Centre, SCK•CEN & Centre For Ethics and Value Inquiry, Faculty of Philosophy, University of Ghent). 
Scientific Conclusions of the Workshop Sarah Baatout (SCK•CEN, BE)
Closure of the Workshop Frank Hardeman (SCK•CEN, BE)